Bias in Human Lymphatic Filariasis Lymphocyte Responsiveness and Cytokine Transmission Intensity Determines
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Regulatory T Cells in Human Lymphatic Filariasis: Stronger Functional Activity in Microfilaremics
Infection with filarial parasites is associated with T cell hyporesponsiveness, which is thought to be partly mediated by their ability to induce regulatory T cells (Tregs) during human infections. This study investigates the functional capacity of Tregs from different groups of filarial patients to suppress filaria-specific immune responses during human filariasis. Microfilaremic (MF), chronic...
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تاریخ انتشار 2001